In modern pharmaceutical packaging, two major trends are becoming more apparent: single-dose packaging and automated packaging. The drug in the unit dose package is equivalent to a single dose. They may also contain sufficient doses only within 24 hours.

In addition to pharmaceutical packaging, blister packaging is also used in food, cosmetics, toys, and other industries. If the blister package is not well sealed, it is easy to shorten the shelf life of the product, which in turn causes deterioration of the contents.

According to Wikipedia, "Opioids are substances that act on opioid receptors to produce morphine-like effects. Medically they are primarily used for pain relief, including anesthesia." Opioids have a significant tendency to have side effects, and such drug itself has serious problems of substance abuse and addiction.

Compared with bottled tablet medicine, blister packs have the greatest advantage of being easy to carry and can reduce contamination during drug handling and taking. However, as a patient who is on a regular basis, they need a large single dose, which makes the unit cost of the blister pack significantly higher than that of the bottled medicine.

With the continuous improvement of the packaging industry, new types of packaging materials and packaging products have emerged in the market. A blister package capable of sealing a product between a blister formed by a transparent plastic sheet and a bottom plate is a packaged product that has been developed according to market demand.

Aluminum-plastic blister packaging for pharmaceuticals has developed rapidly in recent years. Because of its long shelf life and portability, this package is increasingly popular with pharmaceutical companies and consumers. The tropical aluminum blister package is a packaging form specially developed to enhance the barrier properties of aluminum-plastic blister packaging, and is particularly suitable for packaging food, medicine, health care products and the like which have high barrier performance requirements.

The original inventor of this packaging cannot be verified, and the earliest record we can find now is the patent US2415859A registered by Enock Ancker on Feb 18, 1947, Then in 1971, M Nichols submit an Apparatus for inserting tablets into blister packages(patent US3724165A).

Blister packaging is a widely used packaging form. For different blister packaging, the blister, cavity, and box are different, as well as the shape, it will be different based on different products to be packed. Also, there are various substrates, materials and heat-sealing method for blister packaging.

Blister packaging refers to a packaging method of highly efficient and low-cost. The product is usually sealed between the blister and the bottom plate (generally made of cardboard, plastic film or sheet, aluminum foil or a composite thereof) by heat sealing or other methods. For taking tablets, squeeze blister by hand and tablets will come out from the aluminum foil. Therefore, blister packaging is also called as foamed packaging or press-through packaging.